
Injections for Osteoarthritis
Interventional Pain Management for Osteoarthritis
Mechanisms of Action
These type of injections involves a gel-like substance designed to support joint function. When administered into the joint by a health care professional, it can help to:
- Improve lubrication and shock absorption
- Reduce inflammation within the joint
- Provide pain relief
- Support the production of healthier joint fluid
- Protect remaining cartilage
These injections may be used in joints such as the knee, hip, ankle, foot, shoulder, elbow, wrist, and base of the thumb.
The Treatment
This therapy is often more effective when the joint is less swollen or inflamed. For this reason, any excess fluid may be aspirated and sometimes treated with cortisone several weeks before starting.
- Injections are performed under CT guidance and sterile conditions by a doctor
- Treatment usually involves a series of three injections, spaced about two weeks apart. Each appointment takes approximately 10–15 minutes, and patients are generally able to drive afterward
- At the first appointment, any excess joint fluid may be removed using the same needle before the injection is given
- A short period of relative rest (around 48 hours) is recommended after each injection, avoiding activities that aggravate symptoms
- Benefits are typically most noticeable after 6–8 weeks, with relief sometimes lasting more than 6 months. Treatment can usually be repeated up to twice a year if needed
Side Effects and Risks
- Temporary joint swelling or stiffness
- Mild pain or bruising at the injection site
- Rarely, infection. If fever, increasing pain, swelling, redness or warmth occur in the week following an injection, contact your doctor immediately
If you have any concerns regarding this treatment, please speak with your doctor or contact our clinic.
This therapy is supported in clinical guidelines from international musculoskeletal and rheumatology societies for use in the management of osteoarthritis symptoms and is one of several options that may be considered for managing joint symptoms as part of an individualised care plan.

Find a Clinic
We have multiple locations across Victoria, Western Australia, and South Australia.
Fees and billing
In most instances, we bulk bill to Medicare, but it is important to check with your individual clinic prior to your service.